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Fig. 5 | Diagnostic Pathology

Fig. 5

From: Cytokeratin-positive interstitial reticulum cell (CIRC) tumor in the lymph node: a case report of the transformation from the epithelioid cell type to the spindle cell type

Fig. 5

Relapsed cytokeratin-positive interstitial reticulum cell (CIRC) tumor and small cell carcinoma at autopsy. a Macroscopic findings of the CIRC tumor invading into the superior vena cava (arrow). b Microscopic findings of the CIRC tumor composed of spindle-shaped cells with a loose flow. Inset: high-magnification view of atypical multinucleated cells. c Small cell carcinoma showing typical histological findings on autopsy. Tumor cells had a high N/C ratio and formed focal molding structures. This finding was completely different from that of CIRC tumors

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