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Fig. 4 | Diagnostic Pathology

Fig. 4

From: Lymphoepithelioma-like carcinoma in liver not associated with Epstein-Barr virus: a report of 3 cases and literature review

Fig. 4

Preoperative MRI findings and microscopic findings of the resected specimen. MRI showing a tumor of approximately 2.7 × 2.2 cm in segment VIII, hypointense on T1-weighted images (a). An enlarged lymph node can be seen on the upper margin of the pancreas, beside the common hepatic artery, approximately 5.2 × 3.4 cm in size (b). An enlarged lymph node is present beside the portal vein, behind the duodenal ligament (c). Proliferation of atypical large cells, with large nuclei and prominent nucleoli, and characterized by an eosinophilic cytoplasm. Epithelial cells were surrounded by a dense lymphoid stroma extending inside the tumor (d, HE, × 200), (e, HE, × 400), (f, HE, × 400). Immunohistochemical staining for AFP and CK19 is positive (g, HE, × 200), (h, HE, × 200). Immunohistochemical staining for Arg and EBER is negative (i, HE, × 200)

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