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Table 2 Pathological classification and immunohistochemical markers of the 3 patients

From: Lymphoepithelioma-like carcinoma in liver not associated with Epstein-Barr virus: a report of 3 cases and literature review

Case

Diagnosis

Classification

Lymph node

TNM stage

Edmondson-Steiner stage

AFP

Hepatocyte

Arg

CK7

CK19

CK18

EBER ISH

First

LELC

Hepatocellular&Cholangio-carcinoma differentiation

N

T1N0M0

III (poorly differentiated)

–

+

–

+

+

+

–

Second

LELC

Hepatocellular

N

T1N0M0

III (poorly differentiated)

–

–

–

–

–

+

–

Third

LELC

Hepatocellular

P

T1N1M0

III (poorly differentiated)

1+

–

–

–

+

+

–

  1. LELC lymphoepithelioma-like carcinoma, − negative, + positive, AFP a-fetoprotein, EBER EBV-encoded RNA, ISH in situ hybridization, arg arginase
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Diagnostic Pathology

ISSN: 1746-1596

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