References | Sex | Age, years | Region | HBV | HCV | AFP, > 7 ng/mL | No. of lesions | Size, mm | Treatment | FU, mo. | Outcome | Immunohistochemical markers |
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AFP | Hepatocyte | CK7 | CK19 | CK18 | EBER |
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First case | M | 62 | Asian | + | – | + | 1 | 28 | LR | 13 | AWOD | – | + | + | + | + | – |
Filotico et al [50] | F | 62 | NA | + | – | + | 1 | 50 | LR | NA | NA | + | + | + | + | NA | NA |
Wei et al [51] | M | 40 | Asian | + | – | + | 1 | 21 | LR | 30 | AWOD | – | + | + | + | + | – |
- F female, M male, + positive, − negative, HBV hepatitis B virus, HCV hepatitis C virus, NA not available, No. number, AFP a-fetoprotein, AWOD alive without disease, FU follow-up, mo. months, LR liver resection, EBER EBV-encoded RNA