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Fig. 3 | Diagnostic Pathology

Fig. 3

From: T-cell lymphoma with a granulomatous lesion of the lungs after autologous hematopoietic stem cell transplantation for Epstein–Barr virus-positive diffuse large B-cell lymphoma: a unique rare case of metachronous B-cell and T-cell lymphoma

Fig. 3

Pathologic findings of the video-assisted thoracoscopic surgery (VATS) specimen. a In the lung tissue, multiple nodules were observed. b, c High power views showing notable infiltration of lymphocytes with multiple granulomas (*). d The lymphocytes were small to medium-sized with slight nuclear irregularities. b-d Higher magnification of the boxed area in (a), (b), and (c), respectively. e, f The lymphocytes were positive for CD3 (e) and focally positive for CD20 (f). g The lymphocytes destructively infiltrated the alveolar epithelium (AE1/AE3). h Epithelioid cells of the granulomas were positive for CD68. i Some of the lymphocytes were positive for EBER. j-l The lymphocytes were positive for CD4 (j) and negative for BCL-6 (k) and CD10 (l). c, e-l Serial sections. Scale bar: 7 mm (a), 1 mm (b), 150 μm (c, e-l), 60 μm (d)

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