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Table 1 Clinical data of Hepatic Hemangioendothelioma HE (n = 7)

From: Hepatic epithelioid hemangioendothelioma: case series of a rare vascular tumor mimicking metastases

S. No

Year of diagnosis

Age (years)

Gender

Location in Liver

Imaging Findings

Treatment given

Follow up

1

2006

20

F

Right Lobe

Single diffuse mass in right lobe of liver? HCC

Chemotherapy

Died of disease within 6 months of diagnosis. No known history of metastases.

2

2007

38

M

Right Lobe

Single diffuse mass in right lobe of liver? HCC

Chemotherapy

Died of disease in 2013. Received 3 cycles of chemotherapy (Carboplatin) in 2007 but did not respond. Developed lung metastasis in 2012. Histopathology of lung metastases not done.

3

2010

32

M

Both lobes of liver

Multiple masses in both lobes of liver.? Primary? Secondary

Not Known

Lost to follow up

4

2015

70

F

Both lobes of liver

Multiple masses in both lobes of liver. HCC? Metastasis

None

Died of disease in 2017. No chemotherapy given. Symptomatic treatment only. Lung metastases present on PET scan at the time of diagnosis. Histopathology of lung metastases not done.

5

2017

39

F

Both lobes of liver

Multiple masses in both lobes of liver

Not Known

Lost to follow up

6

2018

76

M

Both lobes of liver

Multiple masses in both lobes of liver

Chemotherapy

Alive with disease. On Tab Pazopanib since December 2018 to date. On PET scan

-Lung metastases detected in March 2019

-Omental metastases detected in December 2019

-Colonic metastases detected in January 2020.

Histopathology of metastatic lesions not done.

7

2019

45

F

Both lobes of liver

Multiple masses in both lobes of liver

None

Alive with disease. No metastasis. No chemotherapy or any other treatment given.