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Table 3 Pathological and immunohistological findings of 27 colorectal T/NK cell lymphoma patients

From: Endoscopic and clinicopathological characteristics of colorectal T/NK cell lymphoma

 

MEITL (n = 9)

ATLL (n = 11)

Other group (n = 7)

Total (n = 27)

Histological findings

 Monomorphic medium-sized cell

9 (100%)*

1 (9%)*

0 (0%)

10 (37%)

 Pleomorphic medium-sized cell

0 (0%)*

8 (73%)*

3 (42%)

11 (41%)

 Monomorphic large cell

0 (0%)

0 (0%)

4 (57%)

4 (15%)

 Pleomorphic large cell

0 (0%)

2 (18%)

0 (0%)

2 (7%)

Increased atypical IELs in tumors

7/8 (88%)

6/10 (60%)

0/5 (0%)

13/23 (57%)

Lymphocytic proctocolitis

5 (56%)**

1 (9%)**

0 (0%)

6 (22%)

Tumor cell markers

 CD3

9 (100%)

11 (100%)

5 (71%)

25 (93%)

 CD4

1 (11%)*

9 (82%)*

3 (42%)

13 (48%)

 CD8

9 (100%)*

2 (18%)*

2 (29%)

13 (48%)

 CD25

0/8 (0%)*

11 (100%)*

2/6 (33%)

13/25 (52%)

 CD56

8 (89%)*

1 (9%)*

1 (14%)

10 (37%)

 CD30

0/8 (0%)

2/9 (22%)

4 (57%)

6/24 (25%)

 CD194 (CCR4)

0/7 (0%)*

9/9 (100%)*

0 (0%)

9/23 (39%)

 CD103

6 (67%)

4 (36%)

1 (14%)

11 (41%)

 TIA-1

9 (100%)*

0/8 (0%)*

6 (86%)

15/24 (63%)

EBERs

0 (0%)

0 (0%)

4 (57%)

4 (15%)

  1. * P < 0.01; ** P < 0.05; IELs Intraepithelial lymphocytes