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Table 3 Pathological and immunohistological findings of 27 colorectal T/NK cell lymphoma patients

From: Endoscopic and clinicopathological characteristics of colorectal T/NK cell lymphoma

  MEITL (n = 9) ATLL (n = 11) Other group (n = 7) Total (n = 27)
Histological findings
 Monomorphic medium-sized cell 9 (100%)* 1 (9%)* 0 (0%) 10 (37%)
 Pleomorphic medium-sized cell 0 (0%)* 8 (73%)* 3 (42%) 11 (41%)
 Monomorphic large cell 0 (0%) 0 (0%) 4 (57%) 4 (15%)
 Pleomorphic large cell 0 (0%) 2 (18%) 0 (0%) 2 (7%)
Increased atypical IELs in tumors 7/8 (88%) 6/10 (60%) 0/5 (0%) 13/23 (57%)
Lymphocytic proctocolitis 5 (56%)** 1 (9%)** 0 (0%) 6 (22%)
Tumor cell markers
 CD3 9 (100%) 11 (100%) 5 (71%) 25 (93%)
 CD4 1 (11%)* 9 (82%)* 3 (42%) 13 (48%)
 CD8 9 (100%)* 2 (18%)* 2 (29%) 13 (48%)
 CD25 0/8 (0%)* 11 (100%)* 2/6 (33%) 13/25 (52%)
 CD56 8 (89%)* 1 (9%)* 1 (14%) 10 (37%)
 CD30 0/8 (0%) 2/9 (22%) 4 (57%) 6/24 (25%)
 CD194 (CCR4) 0/7 (0%)* 9/9 (100%)* 0 (0%) 9/23 (39%)
 CD103 6 (67%) 4 (36%) 1 (14%) 11 (41%)
 TIA-1 9 (100%)* 0/8 (0%)* 6 (86%) 15/24 (63%)
EBERs 0 (0%) 0 (0%) 4 (57%) 4 (15%)
  1. * P < 0.01; ** P < 0.05; IELs Intraepithelial lymphocytes
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