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Fig. 3 | Diagnostic Pathology

Fig. 3

From: Giant lung metastasis of NRAS-mutant melanoma in a 24-year-old patient with a history of BRAF-mutant conventional melanoma harboring Spitzoid morphology: a case report

Fig. 3

Lung metastatic melanoma – predominantly spindle cell component (a H&E stain 200x); epitheloid cell component; no melanin pigment present (b H&E staining, 200x). The neoplastic cells are melan A positive, admixt lymphocytes are negative (c IHC 100x) and MITF positive (d IHC 200x). S100 protein and S0X10 were also strongly positive, whereas HMB45 was negative (not shown)

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