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Fig. 4 | Diagnostic Pathology

Fig. 4

From: Circ_0001421 facilitates glycolysis and lung cancer development by regulating miR-4677-3p/CDCA3

Fig. 4

Circ_0001421 regulated LC cell progression by adsorbing miR-4677-3p in LC cells. a The expression of miR-4677-3p in H1299 and A549 cells transfected with anti-miR-NC or anti-miR-4677-3p was detected by qRT-PCR. b-g H1299 and A549 cells were transfected with si-NC, si-circ_0001421, si-circ_0001421 + anti-miR-NC or si-circ_0001421 + anti-miR-4677-3p. b MTT assay was employed to analyze cell proliferation. c-d Cell migration and invasion were evaluated by Transwell assay. e-f Glucose consumption and lactate production were assessed by a Glucose assay kit and a Lactic Acid assay kit. g Western blot was used to check the protein expression of HK2. *P < 0.05

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