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Table 2 Histological features of SPN in patients under 20 years of age (n = 29)

From: Clinicopathological and immunohistochemical study of 29 cases of solid-pseudopapillary neoplasms of the pancreas in patients under 20 years of age along with detailed review of literature

Histological features

Resection specimens

(n = 20)

Incision biopsies (n = 9)

Number of cases present

Percentage (%)

Number of cases present

Percentage (%)

Pseudopapillary architecture

20

100%

9

100%

Solid areas

20

100%

9

100%

Eosinophilic cytoplasm

16

80%

7

77.7%

Myxoid stroma

16

80%

7

77.7%

Hemorrhage

15

75%

7

77.7%

Infarction

14

70%

6

66.7%

Fibrosis

14

70%

6

66.7%

Foamy/ hemosiderin laden macrophages

12

60%

5

55.5%

Clear cells

9

45%

4

44.4%

Hyaline globules

6

30%

3

33.3%

Necrosis

8

40%

4

44.4%

Cholesterol clefts

7

35%

3

33.3%

Cystic degeneration

2

10%

1

11.1%

Microcystic change

5

25%

2

22.2%

Nuclear grooves

5

25%

2

22.2%

Mitotic activity

5

25%

3

33.3%

Atypical cells

3

15%

2

22.2%

Giant cells

4

20%

2

22.2%

Calcification

3

15%

1

11.1%