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Fig. 2 | Diagnostic Pathology

Fig. 2

From: Nodal histiocytic sarcoma with prominent eosinophilic infiltration: expression of eotaxin-2 on tumor cells

Fig. 2

Cytological and histological findings of the lymph node: Mononuclear and multinuclear neoplastic cells were intermingled in an inflammatory background including several eosinophils (a, Papanicolaou stain; b, May-Grunwald Giemsa stain). These were large and round to oval shape, and the nuclei had some nucleoli. An emperipolesis of small lymphocytes was noted. The tumor had a capsule (Arrowheads), but neoplastic cells broke through it (c). The tumor was composed of large cells which had round to oval or spindle shape with diffuse architecture (d, e), and mitoses (f) and emperipolesis (g) were scattered. Numerous numbers of eosinophils infiltrated into the tumor (h). Bars, 50 μm

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