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Table 1 The expression of IL4Rα and IL13Rα1 according to the histologic subtype of soft-tissue sarcomas

From: Expression of IL4Rα and IL13Rα1 are associated with poor prognosis of soft-tissue sarcoma of the extremities, superficial trunk, and retroperitoneum

Histologic type No. nIL4Rα cIL4Rα nIL13Rα1 cIL13Rα1
positive p positive p positive p positive p
Synovial sarcoma 15 10 (67%) 0.027 12 (80%) < 0.001 8 (53%) 0.010 8 (53%) 0.077
Leiomyosarcoma 13 8 (62%)   8 (62%)   10 (77%)   8 (62%)  
Undifferentiated sarcoma 10 8 (80%)   9 (90%)   7 (70%)   7 (70%)  
Liposarcoma, myxoid 9 0 (0%)   0 (0%)   0 (0%)   1 (11%)  
Liposarcoma, WD 4 1 (25%)   1 (25%)   1 (25%)   0 (0%)  
Liposarcoma, dedifferentiated 3 0 (0%)   0 (0%)   1 (33%)   1 (33%)  
Rhabdomyosarcoma, alveolar 3 1 (33%)   3 (100%)   1 (33%)   1 (33%)  
Rhabdomyosarcoma, embryonal 2 1 (50%)   2 (100%)   0 (0%)   0 (0%)  
Rhabdomyosarcoma, pleomorphic 1 0 (0%)   1 (100%)   0 (0%)   0 (0%)  
Rhabdomyosarcoma, spindle 1 1 (100%)   1 (100%)   1 (100%)   1 (100%)  
Myxofibrosarcoma 6 4 (67%)   3 (50%)   2 (33%)   2 (33%)  
MPNST 5 2 (40%)   1 (20%)   3 (60%)   1 (20%)  
Epithelioid sarcoma 4 3 (75%)   3 (75%)   4 (100%)   4 (100%)  
Ewing sarcoma 4 3 (75%)   3 (75%)   3 (75%)   2 (50%)  
Fibrosarcomaa 4 2 (50%)   4 (100%)   1 (25%)   2 (50%)  
Angiosarcoma 3 3 (100%)   3 (100%)   3 (100%)   2 (67%)  
Low-grade myofibroblastic sarcoma 2 2 (100%)   2 (100%)   0 (0%)   0 (0%)  
  1. Abbreviations: WD Well differentiated, MPNST Malignant peripheral nerve sheath tumor, nIL4Rα Nuclear expression of IL4Rα, cIL4Rα Cytoplasmic expression of IL4Rα, nIL13Rα1 Nuclear expression of IL13Rα1, cIL13Rα1 Cytoplasmic expression of IL13Rα1. aThe four cases of fibrosarcoma consist of one case of infantile fibrosarcoma and three cases of adult fibrosarcoma
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Diagnostic Pathology

ISSN: 1746-1596

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