Table 4 Univariate analysis of GSTM3 expression and clinicopathological factors for DSS and DFS in protein cohort patients with ESCC
Characteristic | Cases | Disease-specific survival (DSS) (%) | P# | Disease-free survival (DFS) (%) | P# | ||
|---|---|---|---|---|---|---|---|
3-year DSS | 5-year DSS | 3-year DFS | 5-year DFS | ||||
Gender | 0.536 | 0.188 | |||||
Male | 137 | 31.4 | 24.4 | 19.3 | 18.2 | ||
Female | 110 | 40.0 | 32.4 | 30.3 | 25.0 | ||
Age | 0.210 | 0.214 | |||||
≤60 | 138 | 37.7 | 32.8 | 31.9 | 23.3 | ||
>60 | 109 | 32.1 | 21.5 | 22.0 | 17.7 | ||
Location | 0.148 | 0.054 | |||||
Upper | 60 | 25.0 | 20.8 | 12.5 | 12.5 | ||
Middle | 161 | 37.9 | 29.3 | 26.3 | 21.3 | ||
Lower | 26 | 42.3 | 35.3 | 37.5 | 37.5 | ||
Differentiation | 0.098 | 0.046 | |||||
Grade 1 | 23 | 52.2 | 52.2 | 43.5 | 36.2 | ||
Grade 2 | 157 | 35.0 | 24.3 | 24.7 | 23.7 | ||
Grade 3 | 67 | 29.9 | 27.9 | 15.8 | 7.9 | ||
pT category | 0.001 | 0.017 | |||||
T1-2 | 84 | 48.8 | 42.0 | 29.7 | 28.3 | ||
T3-4 | 163 | 28.2 | 21.5 | 21.2 | 15.9 | ||
pN category | 0.000 | 0.002 | |||||
N0 | 136 | 45.6 | 35.2 | 29.3 | 24.1 | ||
N1 | 111 | 22.5 | 19.7 | 17.7 | 17.7 | ||
Pathological staging | 0.000 | 0.001 | |||||
I | 13 | 69.2 | 69.2 | 38.5 | 38.5 | ||
II | 149 | 43.0 | 32.7 | 27.8 | 23.3 | ||
III | 85 | 16.5 | 16.5 | 15.4 | 15.4 | ||
GSTM3 expression | 0.070 | 0.006 | |||||
Low | 155 | 31.0 | 22.3 | 18.7 | 15.3 | ||
High | 92 | 42.4 | 37.1 | 33.5 | 30.5 | ||