Table 5 Univariate analysis of prognostic variablesa for DSS and DFS in mRNA cohort patients with ESCC
Characteristic | Disease-specific survival (DSS) | Disease-free survival (DFS) | ||
|---|---|---|---|---|
HR (95% CI) | P | HR (95% CI) | P | |
Gender (female vs. male) | 1.188 (0.752-1.879) | 0.460 | 1.046 (0.688-1.592) | 0.832 |
Age (>60 vs. ≤60) | 1.420 (0.935-2.157) | 0.100 | 1.179 (0.810-1.716) | 0.389 |
Location (lower vs. middle vs. upper) | 0.772 (0.563-1.058) | 0.108 | 0.862 (0.653-1.138) | 0.295 |
Differentiation (G3 vs. G2 vs. G1) | 1.303 (0.965-1.751) | 0.084 | 1.375 (1.054-1.793) | 0.019 |
pT category (T3-4 vs. T1-2) | 1.555 (0.974-2.482) | 0.064 | 1.420 (0.958-2.105) | 0.081 |
pN category (N1-3 vs. N0) | 2.992 (1.928-4.641) | 0.000 | 3.146 (2.129-4.649) | 0.000 |
Pathological staging (III-IV vs. II vs. I) | 2.497 (1.678-3.717) | 0.000 | 2.573 (1.810-3.657) | 0.000 |
GSTM3 expression (high vs. low) | 0.727 (0.477-1.107) | 0.137 | 0.635 (0.435-0.927) | 0.019 |