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Table 3 List of carcinomas with pancreatic acinar cell differentiation reported in the literature

From: Title: pancreatic‐type mixed acinar neuroendocrine carcinoma of the stomach: a case report and review of the literature

Author, year Age Sex Site Diagnosis Metastasis Ectopic pancreas Therapeutic option Adjuvant therapy Outcome
Fukunaga, 2002 [2] 77 F Fundus MAEC None None EMR Alive, 7mo
Sun et al., 2004 [3] 86 F Antrum ACC None None partial gastrectomy NM
Jain et al., 2005 [5] 41 F Body MAEC LN None partial gastrectomy, partial omentectomy Alive, 2 yr
61 M Fundus MAEC LN, Liver None subtotal gastrectomy Dead, 6mo
72 M Body MAEC None None subtotal gastrectomy Dead, 4mo
Mizuno et al., 2007 [6] 73 M Pylorus NAa LN, Liver None pancreaticoduodenectomy Gemcitabine+Cisplatin+ 5-FU Alive, 11mo
Ambrosini-Spaltro et al., 2009 [7] 52 M Antrum ACC None Presence subtotal gastrectomy, omentectomy, cholecystectomy NM NM
Kusafuka et al., 2009 [8] 56 F Body MAEC Peritoneum, Liver, Skin None total gastrectomy, splenectomy, right-half colonectomy S-1 + Cisplatin Dead
Coyne, 2012 [9] 77 F Fundus ACC None None partial gastrectomy Dead, 1mo
Yonenaga et al., 2016 [10] 67 M Body MAEC LN None distal gastrectomy, lymph node dissection S-1 monotherapy Alive, 21mo
63 M Antrum ACC Liver None Gemcitabine+Erlotinib Dead, 5mo
Kim et al., 2017 [11] 54 M Cardia ACC None None laparoscopic wedge resection Alive, 33mo
Fujita et al., 2019 [12] 67 M NM MiNEN None None ESD Alive, 15mo
  1. NM not mentioned
  2. ACC acinar cell carcinoma
  3. MAEC mixed acinar endocrine carcinoma
  4. MiNEN mixed neuroendocrine-non-neuroendocrine neoplasms
  5. EMR endoscopic mucosal resection
  6. ESD endoscopic submucosal dissection
  7. LN lymph nodes
  8. mo months
  9. yr years
  10. NAa, the immunohistochemistry for neuroendocrine markers was not performed