Fig. 1

a Purpuric maculo-papular rash involving trunk, neck and shoulders; b Back lesions with limited epidermal detachment; c-d The papillary and superficial dermis were edematous and populated mainly by perivascular lympho-granulocytic inflammatory infiltrate, with associated granulocyte intraepithelial exocytosis, and irregular spongiosis (blue arrow). Superficial dermal micro-areas of erythrocytic extravasation (yellow arrow) and endothelial “swelling” (green arrow in fig. c and fig.d; at higher magnification in inset on the right) were observed (C:H&E, 8x; D,:H&E, 20x, inset 40x). Legend: H&E = hematoxylin and eosin stain