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Fig. 2 | Diagnostic Pathology

Fig. 2

From: Succinate dehydrogenase deficient gastrointestinal stromal tumor in a three month old boy with a fatal clinical course: a case report and review of literature

Fig. 2

The microscopic features and immunohistochemical stains of the lesion. a: Tumors are distinctive in their multinodular colon wall involvement with interspersed tracts of colon wall smooth muscle (H&E, × 100). b: The tumor cells have a mainly epithelioid cytology with variably eosinophilic cytoplasm. Mitotic images were easy to be seen (H&E, × 400). c: PDGFR was diffusely and strongly positive (× 200). d: The tumor cells were positive for CD117 (× 200). e: The tumor cells lack SDHB expression, but vascular elements were positive (× 400). f: The Ki-67 labelling index (MIB-1 index) reached 30% in the area of greatest concentration (× 200)

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