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Table 2 Summary of histological features of KH cases. (n = 8)

From: Kaposiform Hemangioendothelioma: clinicopathological characteristics of 8 cases of a rare vascular tumor and review of literature

Case #

Tumor size

(cm.)

Percentage of Vascular Nodules

Percentage of Spindle cells

Lymphangioma-like vessels

Mitoses /10 HPFs

Cytoplasmic vacuoles

Microthrombi

Extent/Plane of invasion (Skin, subcutaneous tissue, bone)

Margins

Additional features

1#

5 × 2

5 %

95 %

None

6

Absent

Absent

Muscle

Involved

Sieve-like architecture of nodules

2

1 × 0.5b

> 95 %

< 5 %

None

5

Absent

Absent

Dermis

Involved

Lymphoid follicles, mixed inflammation

3

1.5 × 1a

80 %

20 %

None

7

Present

Absent

Dermis & subcutis

Cannot be assesseda

Hyaline globules

4

3 × 1.5a

> 95 %

None

< 5 %

6

Present

Absent

Soft tissue

Cannot be assesseda

Hemorrhage & Perineural invasion

5

2 × 0.8

80 %

15 %

5 %

4

Absent

Absent

Synovium

Involved

Background fibrosis

6

5.5 × 3.5

70 %

None

30 %

6

Present

Absent

Bone

Involved

Perineural invasion

7

1.5 cm.

80 %

15 %

5 %

6

Present

Present

Pancreas

Tumor free

None

8

2.5 × 1b

90 %

10 %

None

2

Present

Present

Dermis

Cannot be assessedb

None

  1. aTumor was received in multiple fragments
  2. bIncisional biopsy specimen was received