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Table 1 The organs of the training and validation dataset of TUO

From: Diagnosis prediction of tumours of unknown origin using ImmunoGenius, a machine learning-based expert system for immunohistochemistry profile interpretation

Organ Training data Validation data Test data
No. % No. % No %
Ascites (cell block) 19 3.4% 11 2.9% 1 0.6%
Pleural fluid (cell block) 15 2.7% 12 3.1% 0 0.0%
Lymph node 12 2.1% 9 2.4% 8 4.9%
Peritoneum 13 2.3% 8 2.1% 2 1.2%
Pleura 14 2.5% 7 1.8% 2 1.2%
Lung 116 20.6% 75 19.6% 26 15.9%
Liver 55 9.8% 43 11.3% 33 20.1%
Kidney 37 6.6% 31 8.1% 15 9.1%
Breast 17 3.0% 11 2.9% 1 0.6%
Soft tissue 38 6.8% 14 3.7% 6 3.6%
Female genital tract including uterus and vulva, vagina 17 3.0% 12 3.1% 18 10.1
Adnexa 8 1.4% 6 1.6% 0 0.0%
Bladder and urinary tract 7 1.2% 5 1.3% 1 0.6%
Adrenal gland 10 1.8% 5 1.3% 1 0.6%
Prostate 15 2.7% 11 2.9% 0 0.0%
Testis 8 1.4% 5 1.3% 0 0.0%
Pancreas 7 1.2% 4 1.0% 3 1.8%
Stomach 37 6.6% 20 5.2% 9 5.5%
Small intestine 4 0.7% 1 0.3% 5 3.0%
Large intestine and rectum 30 5.3% 23 6.0% 12 7.3%
Gallbladder 3 0.5% 1 0.3% 0 0.0%
Appendix 2 0.4% 1 0.3% 0 0.0%
Brain (CNS) 11 2.0% 6 1.6% 14 8.5%
Meninges 22 3.9% 16 4.2% 0 0.0%
Naso- and oropharynx 13 2.3% 10 2.6% 2 1.2%
Skin 14 2.5% 11 2.9% 1 0.6%
Bone 6 1.1% 5 1.3% 3 1.8%
Thyroid gland 2 0.4% 1 0.3% 0 0.0%
Thymus 3 0.5% 2 0.5% 0 0.0%
Salivary gland 5 0.9% 3 0.8% 0 0.0%
Eye 2 0.4% 0 0.0% 2 1.2%
Total 562 100.0% 382 100.0% 164 100.0%
  1. Abbreviations: TUO Tumor of unknown origin