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Fig. 3 | Diagnostic Pathology

Fig. 3

From: Sialadenoma papilliferum: clinicopathologic, Immunohistochemical, molecular analyses of new five cases and review of the literature

Fig. 3

Pathological manifestations of Sialadenoma papilliferum. a SP shows a biphasic growth pattern with an exophytic papillary component surfaced by a keratotic squamous epithelium (Green arrow) and an endophytic adenomatous component of the underlying lesion (Red arrow) (20x). b Papillary frond surfaced by stratified squamous epithelium is contiguous with columnar ductal epithelium (Red arrow) (100x). c The surface papillary structure of the lumen supported by thin fibrovascular core often protrudes into the lumen (Red arrow) (50x). d The ductal lumen is double-layered, lined by luminal cuboidal to columnar cells (Green arrow) and cuboidal to flattened basal cells (Red arrow) (400x). e Localized enlargement of the cyst and eosinophilic deposition in the lumen (Red arrow) (50x). f Mucinous cells in tumour area (Red arrow) (400x)

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