Fig. 4

Immunohistochemical performance of Pathological manifestations. a CK7 is strongly positive in the luminal cells (100x). b p63 shows strong positive staining in the basal cells (100x). c S-100 shows positive staining in the basal cells (Red arrow) (100x). d Ki67 ranges from 20 to 30% (100x). e The expression of BRAF V600E is observed in both the glandular and squamous components (Red arrow) (100x). f BRAF V600E immunohistochemistry in the third case shows a weak staining (100x)