Table 1 Next-generation sequencing analysis
Gene/Biomarker | Alteration (frequency) |
|---|---|
SMARCA4 | Germline mutation p.R1093* |
APC | Somatic mutation p.R216*(31.46%) |
JUN | Somatic mutation p.K311Sfs*6 (20.77%) & pN85Pfs*21 15.93%) |
NRAS | Wild-type |
KRAS | Wild-type |
BRAF | Wild-type |
PD-L1 | Negative expression |
TNM | 1.68Muts/Mb |
MSA | MSS |
HLA-I | Heterozygous type |