Table 1 Primary sclerosing cholangitis (PSC) patient cohort and liver biopsies

Number of patients

318

Number of patients, male

182 (63%)

Age at diagnosis in years, mean, (range)

34.9 (10–75)

Duration of disease (years) at liver biopsy, mean (range)

3.26 (0–25)

Stage of fibrosis (Metavir, 0–4) in liver specimen, mean, (range)

1 (0–4)

Biopsies with stage 0 (Metavir) fibrosis, %

44.75

Biopsies with stage 1 (Metavir) fibrosis, %

24.59

Biopsies with stage 2 (Metavir) fibrosis, %

19.14

Biopsies with stage 3 (Metavir) fibrosis, %

8.33

Biopsies with stage 4 (Metavir) fibrosis, %

3.19

Plasma ALP (U/l) levels ±3 months from liver biopsy, mean ± SD, (range)

216.75 ± 198.38 (42–1514)