Table 4 The K7-AI model’s results (K7%area) and their correlations with biochemical examinations indicating cholestasis, and the K7-AI model results (K7%area and ln (K7%area)) in correlation with stage of fibrosis, according to Metavir and Nakanuma classifications

Laboratory parameter (plasma tests):

Pearson K7%area (p-value)

Spearman K7%area (p-value)

Pearson ln (K7%area) (p-value)

ln (ALP) (alkaline phosphatase) (U/l)

0.290 (p = 0.002)

0.359 (p < 1.001–05)

0.348 (p = 1.71e-4)

ln (GT) (gamma-glutanyl transpeptidase) (U/l)

0.275 (p = 0.275)

0.204 (p = 0.112)

0.216 (p = 0.092)

ln (Bil) (non-conjugated bilirubin) (μmol/l)

0.264 (p = 0.012)

0.253 (p = 0.016)

0.273 (p = 0.009)

Fibrosis stage:

Pearson-correlation K7%area; p-value

Spearman-correlation K7%area; p-value

Pearson-correlation ln (K7%area); p-value

Nakanuma score (0–3)

0.289; p < 3.7e-4

0.467; p < 4.004e-12

0.457; p < 1.267e-11

Metavir score (0–4)

0.242; p < 9.1e-4

0.441; p < 3.438e-10

0.437; p < 5.083e-10