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Fig. 6 | Diagnostic Pathology

Fig. 6

From: LncRNA GAS5 modulates the progression of non-small cell lung cancer through repressing miR-221-3p and up-regulating IRF2

Fig. 6

Regulatory effects of GAS5 and miR-221-3 on IRF2 expression in NSCLC cells. a The binding sequence between miR-221-3p and IRF2 3’UTR. b Binding sites between miR-221-3p and IRF2 3’UTR were verified using dual-luciferase reporter gene experiments. c, d The regulatory effects of miR-221-3p and GAS5 on IRF2 mRNA expression in NSCLC cells were detected by qPCR. e, f The effects of miR-221-3 and GAS5 on IRF2 protein expression in NSCLC cells were detected by Western blot. ** and *** represent p < 0.01 and p < 0.001, respectively

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