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Fig. 4 | Diagnostic Pathology

Fig. 4

From: Detection of BCOR gene rearrangement in Ewing-like sarcoma: an important diagnostic tool

Fig. 4

Genomic rearrangement in BCS. A Detection of BCOR gene rearrangement by fluorescence in situ hybridization, split signals of the BCOR gene (left, white arrows), normal signals of the BCOR gene (right up, male; right down, female). B Identification of the BCOR-CCNB3 fusion transcripts by RT-PCR (M: marker; 1: negative control; 2: positive control; 3–9: case1–6, 8). C Schematic of the genomic breakpoint sequence in a representative case (Case 3). Original total magnification × 1000 (A)

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