Fig. 3

Identification and functional enrichment of hub modules. A Heatmap showing associations between the module characteristic genes and immune cell infiltration. B CD8⁺ T cell infiltration in HCC samples and adjacent non-tumor samples from the GSE14520 dataset. Normal and Tumor indicate adjacent non-tumor samples and HCC samples, respectively. C CD8⁺ T cell infiltration in HCC samples and adjacent non-tumor samples from the GSE54236 data set. Normal and Tumor indicate adjacent non-tumor samples and HCC samples, respectively. D Significantly enriched GO terms. GO: Gene Ontology; BP: Biological process; CC: Cell composition; MF: Molecular function. E Significantly enriched KEGG pathways. For KEGG analysis, different colors represent different signaling pathways. KEGG, Kyoto Encyclopedia of Genes and Genomes