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Fig. 1 | Diagnostic Pathology

Fig. 1

From: Lipoprotein glomerulopathy associated with the Osaka/Kurashiki APOE variant: two cases identified in Latin America

Fig. 1

Kidney biopsy. Case 2. A, B, C, D Glomerulus with increased mesangial matrix and cellularity, displaying open capillary loops filled with amorphous, acellular, lipidic and pale material observed on PAS, Picrosirius, Masson’s trichrome and Jones silver methenamine staining, respectively; and E Oil Red staining showing lipidic material within the glomerular capillaries (400X). Case 1. F Toluidine blue staining revealing glomerulus with intense luminal deposition of lipidic material. Cases 2 (G) and 1 (H): Transmission electron microscopy obtained after re-inclusion of paraffin-embedded material in resin, stained with osmium tetroxide and ruthenium red, showing lipoprotein pseudo-thrombi constituted of vacuolized material inside the capillary loops (16.500X magnification)

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Diagnostic Pathology

ISSN: 1746-1596

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