Fig. 2

Histopathology of central MEC arising from a GOC of the mandible in a biopsy specimen. a The biopsy showed an enlarged unilocular cyst with thick fibrous connective tissue, along with a polycystic lesion on one side (black arrows). b Numerous microcysts and mucous goblet cells were observed in the cyst lining epithelium. c Mucous goblet cells were positive for mucicarmine staining. d Eosinophilic cuboidal cells were seen within the lining epithelium. e Ciliated cells were scattered within the non-keratinized squamous epithelial cells. f The cyst wall consisted of fibrous connective tissue and non-keratinizing squamous epithelium in the GOC part (black square in a). g Several cystic nests, which contained eosinophilic materials, were also found in the central MEC parts (yellow square in a). Hematoxylin-eosin (a–b, d–g), mucicarmine stain (c), Scale bars, 1 mm (a), 20 μm (b–e), 100 μm (f–g)