Fig. 4

The surgical specimen after the biopsy showing central MEC. a The operative surgical specimen of the mandible. The specimen was cut before decalcification in a part (yellow line). The tumor expanded to the submucosal area from the mandibular bone in the cut surface (b) Tumor with many cystic spaces expanded into the submucosal area of the gingiva. c, d Immunoreactivity for CK18 was positive in central MEC, but negative for CK13. Scale bars, 10 mm (a), 200 μm (b–d)