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Fig. 2 | Diagnostic Pathology

Fig. 2

From: miR-3113-5p, miR-223-3p, miR-133a-3p, and miR-499a-5p are sensitive biomarkers to diagnose sudden cardiac death

Fig. 2

Representative photographs of cleaved-Caspase3 (cl-Casp3), CD31, and CD68 expression in heart tissues stained by immunohistochemistry. SCD-positive autopsy group showed increases in the expression of cl-Casp3 (cytoplasm positivity in apoptotic cells), CD31 (lumen positivity), and CD68 (a marker of macrophage), whereas fatal injury and CO intoxication cases were absent from strong positivity of the above markers. SCD-negative autopsy cases showed patchy positivity of cl-Casp3 and dim CD31 signal, and were absent of CD68 positivity. Scale bar = 200 μm

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Diagnostic Pathology

ISSN: 1746-1596

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