Skip to main content
Fig. 2 | Diagnostic Pathology

Fig. 2

From: WHO/ISUP grading of clear cell renal cell carcinoma and papillary renal cell carcinoma; validation of grading on the digital pathology platform and perspectives on reproducibility of grade

Fig. 2

(A) CCRCC (H&E x10, inset H&E x40) case where all three pathologists agreed on ISUP grading (grade 3) on both DP and GS1 review. (B) PRCC (H&E x10, inset H&E x40) case which was upgraded by one pathologist by two grades (ISUP grade 1 on DP to 3 on GS1 review), and downgraded by one pathologist (ISUP grade 3 to 2). (C) CCRCC (H&E x10, inset H&E x40) case which was downgraded from ISUP grade 3 on DP to 2 on GS1 review by one pathologist, upgraded from ISUP 2 to 3 by one pathologist, and graded 3 by a third pathologist on both DP and GS1 review. (D) CCRCC (H&E x10, inset H&E x40) case which was upgraded from ISUP grade 2 on DP to 3 on GS1 review by two pathologists, and graded as ISUP 3 by a third pathologist on both DP and GS1 review. CCRCC = clear cell renal cell carcinoma, PRCC = papillary renal cell carcinoma, DP = digital pathology, GS = glass slide, ISUP = International Society of Urological Pathology.

Back to article page

Diagnostic Pathology

ISSN: 1746-1596

Contact us