Table 2 The changes of lymphocyte subsets, thyroid function indexes and PD-1 among NG&HT, PTC&noHT and PTC&HT

Total T(%)

60.92 ± 6.31

63.49 ± 8.49

62.38 ± 7.63

0.565

0.451

0.706

0.387

CD3⁺CD4⁺(%)

31.82 ± 3.39

37.24 ± 6.79

36.39 ± 5.93

0.132

0.047

0.093

0.523

CD3⁺CD8⁺(%)

26.10 ± 7.40

22.99 ± 7.40

22.56 ± 5.46

0.443

0.273

0.201

0.614

CD4⁺/CD8⁺(%)

1.21[0.90,1.78]

1.64 [1.19,2.37]

1.69 [1.25,2.18]

0.235

CD4⁺ HLA-DR⁺(%)

7.37 ± 3.90

5.96 ± 2.06

6.34 ± 2.10

0.266

0.128

0.417

0.250

CD8⁺ HLA-DR⁺(%)

7.98 ± 3.96

6.6.5 ± 3.88

6.60 ± 2.84

0.633

0.376

0.341

0.834

CD8⁺CD38⁺(%)

8.96 ± 8.01

5.42 ± 2.81

5.70 ± 2.82

0.032*

0.009*

0.016*

0.694

NK(%)

23.05 ± 8.70

17.24 ± 8.20

18.23 ± 8.47

0.233

0.100

0.186

0.484

B(%)

10.85 ± 2.89

14.58 ± 5.10

15.33 ± 4.71

0.080

0.075

0.029*

0.281

T3(nmol/L)

1.21[1.15, 1.24]

1.20[1.07, 1.28]

1.16[1.06, 1.30]

0.472

T4(nmol/L)

8.50[6.90,9.00]

8.20 [6.44,9.10]

8.20 [6.00,9.25]

0.991

FT3(pmol/L)

3.28 ± 0.23

3.39 ± 0.37

3.32 ± 0.48

0.568

0.563

0.873

0.331

FT4(pmol/L)

1.29 ± 0.17

1.30 ± 0.18

1.35 ± 0.20

0.350

0.882

0.466

0.162

TSH (μIU/mL)

1.98[1.49, 4.69]

1.43[1.02, 1.94]

1.79[1.17, 2.46]

0.155

TGAb (IU/mL)

218.0[29.0,489.0]

18.0[15.00,23.0]

125.0[33.0,243.5]

0.000*

0.000*

0.543

0.000*

TPO (IU/mL)

996.5[291.0,1300.0]

28.0[28.0,37.5]

258.0[36.0,909.0]

0.000*

0.001*

0.165

0.000*

CD3⁺ PD-1⁺ (%)

7.70 ± 2.10

10.35 ± 4.13

13.31 ± 5.04

0.000*

0.042*

0.006*

0.000*

CD3⁺CD4⁺PD-1⁺ (%)

4.97 ± 1.63

7.12 ± 2.93

9.24 ± 3.20

0.000*

0.049*

0.003*

0.000*

CD3⁺CD8⁺PD-1⁺ (%)

3.43 ± 1.35

4.53 ± 2.13

5.51 ± 2.22

0.012*

0.138

0.011*

0.005*

TILS(%)

1(10.0%)

17(20.5%)

24(49.0%)

0.001*

CD3 POSITIVE(%)

1(10.0%)

13(15.6%)

21(42.9%)

0.001*

PD-1 POSITIVE(%)

0

12(14.5%)

14(28.6%)

0.038*