From: Assessment of H3K27me3 immunohistochemistry and combination of NF1 and p16 deletions by fluorescence in situ hybridization in the differential diagnosis of malignant peripheral nerve sheath tumor and its histological mimics
NF1 and/or p16 deletion
Histology
Total, n (%)
Present, n (%)
Absent, n (%)
P-value
Low-grade MPNST
7 (12.7)
4 (57.1)
3 (42.9)
0.022
High-grade MPNST
48 (87.3)
45 (93.8)
3 (6.2)