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Fig. 1 | Diagnostic Pathology

Fig. 1

From: Long non-coding RNA DUXAP8 elevates RCN2 expression and facilitates cell malignant behaviors and angiogenesis in cervical cancer via sponging miR-1297

Fig. 1

DUXAP8 is aberrantly highly expressed in CC and silencing DUXAP8 suppresses the malignant phenotypes of CC cells. A. The expression of DUXAP8 in CC cell lines and normal cervical cell line was detected by RT-qPCR analysis. B. The inhibitory efficiency of sh-DUXAP8#1/2 was detected by RT-qPCR. C-D. Colony formation assay and EdU assay were performed to test cell proliferation ability after transfecting sh-DUXAP8#1/2 into caSki and HeLa cells. E. Flow cytometry analysis was conducted to assess the apoptotic rate of cells with or without DUXAP8 inhibition. F. Transwell migration assay determined the migration of caSki and HeLa cells after silencing DUXAP8. G. The impact of DUXAP8 silence on the invasion of caSki and HeLa cells was evaluated by transwell invasion assay. H. Tube formation assays were performed to explore angiogenesis ability after silencing DUXAP8 in HUVECs co-cultured with the CM of indicated caSki and HeLa cells. **P < 0.01

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Diagnostic Pathology

ISSN: 1746-1596

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