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Fig. 3 | Diagnostic Pathology

Fig. 3

From: Long non-coding RNA DUXAP8 elevates RCN2 expression and facilitates cell malignant behaviors and angiogenesis in cervical cancer via sponging miR-1297

Fig. 3

RCN2 is the potential downstream target of miR-1297. A. The expression levels of potential target genes for miR-1297 were evaluated by RT-qPCR after overexpressing miR-1297 in HeLa cells. B. The expression status of RCN2 in CC cell lines and non-tumor control cells was determined by RT-qPCR. C. Putative binding sites between miR-1297 and RCN2 predicted by starBase. D. Luciferase reporter assays were performed in caSki and HeLa cells to determine the physical interaction between miR-1297 and RCN2. E. RIP assays were performed to study the molecular relationship of DUXAP8, miR-1297 and RCN2. F-G. RT-qPCR was performed to study the effects of DUXAP8 suppression on the expression of miR-1297 or RCN2, respectively. **P < 0.01

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Diagnostic Pathology

ISSN: 1746-1596

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