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Fig. 3 | Diagnostic Pathology

Fig. 3

From: Periostin expression and its supposed roles in benign and malignant thyroid nodules: an immunohistochemical study of 105 cases

Fig. 3

Immunohistochemical staining results for other thyroid tumor markers. In microcarcinoma, cancer cells exhibited strong positivity for galectin-3 (Gal-3) (A) and nuclear positivity for cyclin D1 (B). In papillary carcinoma, the cytoplasm of cancer cells was diffusely positive for Gal-3 (C). Undifferentiated carcinoma showed cytoplasmic immunopositivity for Gal-3 with a mosaic-like pattern (D). In papillary carcinoma, the luminal side of papillary structures was positive for Hector Battifora mesothelial 1 (HBME-1) (E), and tumor cells were diffusely positive for cytokeratin 19 (F). In undifferentiated carcinoma, cancer cells were diffusely positive for Ki-67 (G), whereas tumor cells in papillary carcinoma were sporadically positive for Ki-67 (H)

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Diagnostic Pathology

ISSN: 1746-1596

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