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Fig. 3 | Diagnostic Pathology

Fig. 3

From: Diagnostic performance of Midkine ratios in fine-needle aspirates for evaluation of Cytologically indeterminate thyroid nodules

Fig. 3

Diagnostic value of midkine (MK)/thyroglobulin (TG) and MK/free thyroxine (FT4) ratios for papillary thyroid carcinoma (PTC). Receiver operating characteristic curves were drawn to assess the diagnostic utility of the (a) MK/TG ratio and the (b) MK/FT4 ratio in preoperatively distinguishing PTCs from benign thyroid nodules. The areas under the curve (AUC) for the MK/TG and MK/FT4 ratios were 0.719 (P = 0.001) and 0.677 (P = 0.006), respectively, with no significant difference (P = 0.896). The cut-off values of MK/TG and MK/FT4 were 55.57 ng/mg (sensitivity 58%, specificity 87%, accuracy 62%) and 0.11 μg/pmol (sensitivity 44%, specificity 91%, accuracy 50%), respectively

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Diagnostic Pathology

ISSN: 1746-1596

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