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Table 6 Diagnostic utility comparison of MK ratios in combination with FNAC

From: Diagnostic performance of Midkine ratios in fine-needle aspirates for evaluation of Cytologically indeterminate thyroid nodules

  Sensitivity (%) Specificity (%) aPPV (%) bNPV (%) Accuracy (%)
FNA 91 100 100 67 92
MK/TG (ng/mg) 36 100 100 22 46
MK/FT4 (μg/pmol) 18 100 100 18 31
FNA + MK/TG (ng/mg) 91 100 100 67 92
FNA + MK/FT4 (μg/pmol) 95 100 100 80 96
  1. a PPV positive predictive value, b NPV negative predictive value