Fig. 9
Schematic drawing of a tumor with PD-L1 staining. There are 37 tumor cells, 14 of which are depicting membrane staining (middle part of the drawing). In addition, 10 of the tumor immune cells, including one macrophage, are positive for PD-L1 (lower right-hand corner). Based on this, tumor positive score (TPS) and combined positive score (CPS) can be calculated.
\(\text{TPS}=\frac{(No.positvetumorcells)14}{\left(No.viabletumorcells\right)37}\times100=37.8\)
\(\text{CPS}=\frac{(No.allpositvecells)24}{\left(No.viabletumorcells\right)37}\times100=64.8\)