Expression of FRS2 in atypical lipomatous tumor/well-differentiated liposarcoma and dedifferentiated liposarcoma: an immunohistochemical analysis of 182 cases with genetic data

Table 3 Sensitivity and specificity of FRS2 immunostaining in diagnosing ALT/WDLs and DDLs

Tumor type	FRS2
	≥1+		≥2+
	Sensitivity	Specificity	Sensitivity	Specificity
ALT/WDL/DDL VS. control group	94.0%	73.5%	66.0%	96.9%
ALT/WDL VS. BAT & normal adipose tissue	91.2%	80.0%	54.9%	100%
DDL VS. other spindle cell tumors	96.7%	65.5%	76.9%	93.1%

ALT/WDL Atypical lipomatous tumor/well-differentiated liposarcoma, DDL Dedifferentiated liposarcoma, BAT benign adipocytic tumor, 1 + weak positivity, 2+ moderate positivity;

ISSN: 1746-1596