Table 1 Genetic alterations of our case and comparison with pure neoplasms
Gene | Our case | Reported altered genes in pure neoplasms | ||
|---|---|---|---|---|
IPMN component | NET component | IPMN | NEN | |
KRAS (MAF) | NM_033360.2 Exon 2, p.G12V (6.1%) | NM_033360.2 Exon 2, p.G12V (4.7%) | GNAS, KRAS, RNF43, KLF4, NBPF1, CDKN2A, APC, TP53, CTNNB1, RMB10, BSN, SETBP1, AJAP1, IGSF3, USP6, STK11, etc. [7, 8] | MEN1, DAXX, ATRX, TSC2, PTEN, PIK3CA, TP53, RB, VHL, MUTYH, BRCA2, CHEK2, ARID1A, BCOR, CDNK1B, KRAS, SMAD4, YY1, MLL3, etc. [9,10,11,12] |
PCK1 (MAF) | NM_002591.3 Exon 14, p.P605H (3.2%) | NM_002591.3 Exon 14, p.P605H (3.0%) | ||
MLL3 (MAF) | NM_170606.2 Exon 10, p.V649M (3.0%) | NM_170606.2 Exon 10, p.V649M (2.5%) | ||