Table 2 Somatic mutations of PCK1 and MLL3 in pancreatic neoplasms in COSMIC database
Genes | CDS Mutation | Pancreatic neoplasm subtypes |
|---|---|---|
PCK1 | c.410G > A, c.865G > A, c.965A > G, c.992G > A, c.1095C > T, c.1187-21G > A, c.1391C > T, c.1656C > G, c.*369G > A, c.*371G > A, c.*373G > A, c.*1678A > G | Ductal carcinoma; some samples with unknown histology subtype |
MLL3 | c.568C > T, c.754C > A, c.1017G > C, c.1042G > A, c.1076G > A, c.1131A > T, c.1139G > T, c.1174C > T, c.1304G > A, c.2183A > C, c.2185A > G, c.2198del, etc. | Ductal carcinoma; PanIN; NET; acinar carcinoma; dysplasia-in situ neoplasm; sarcomatoid carcinoma; samples with unknown histology subtype |