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Table 1 Specimen Processing Data

From: Clinicopathologic correlations of superficial esophageal adenocarcinoma in endoscopic submucosal dissection specimens

Factor

Intramucosal Adenocarcinoma

(n = 30)a

Submucosal Adenocarcinoma

(n = 19)a

Specimen size

< 5 cm

18 (60%)

10 (52.7%)

> 5 cm

12 (40%)

9 (47.4%)

En bloc or Piecemeal

En bloc

27 (90%)

18 (94.7%)

2 pieces

1 (3.3%)

1 (5.3%)

3 pieces

2 (6.7%)

0 (0%)

Orientation marked by gastroenterologist

14 (46.7%)

9 (47.4%)

Gross examination findings

Tumor nodule(s)

20 (66.7%)*

17 (89.5%)**

Ulcerated mucosa

3 (10%)

0 (0%)

No tumor

7 (23.3%)

2 (10.5%)

Peripheral margin involvement (by histology)

Negative

25 (83.3%)

10 (52.6%)

Positive

3 (10%)

2 (10.5%)

Changes in peripheral margin involvement from gross to histologic evaluation

Positive to negative

1 (3.3%)

0 (0%)

Negative to positive

1 (3.3%)

7 (36.8%)

 

Sm1 (< 500 μ)

7 (23%)

4 (21%)

Specimen depth of excision (microscopic)

Sm2 (> 500-1000 μ)

21 (70%)

12 (63%)

 

Sm3 (> 1000 μ)

2 (7%)

3 (16%)

Large pinholes

2 (6.7%)

6 (31.6%)

Tissue folding, producing interpretation problems

3 (10%)

2 (10.5%)

  1. Statistics presented as Frequency (%)
  2. a Data are from 30 endoscopic submucosal dissection (ESD) resections in 24 patients, of which 26 were positive for intramucosal adenocarcinoma
  3. b Data are from 19 ESD resections in 18 patients, of which 18 were positive for submucosal adenocarcinoma
  4. *Multinodularity in 3 specimens
  5. **Multinodularity in 5 specimens