Poor outcomes* | Poor tumor differentiation |
Submucosal depth of invasion > 500 μm (> sm2) | |
Lymphovascular invasion | |
Large vessel invasion | |
Positive margins, specifically, positive deep margin | |
Better outcomes* | Well to moderately differentiated tumor morphology |
Submucosal depth of invasion < 500 μm (sm1) | |
Negative margins, specifically, negative deep margin | |
Absence of lymphovascular invasion |