Table 3 Cox proportional-hazard regression model analysis for for recurrence-free survival
Univariate | Multivariate | |||||
|---|---|---|---|---|---|---|
3-year RFS | 5-year RFS | HR(95%CI) | P | HR(95%CI) | P | |
Age (years) | ||||||
≤65 | 89.50% | 78.77% | reference | reference | ||
>65 | 88.72% | 75.62% | 1.25(0.70~2.23) | 0.452 | 1.41(0.78~2.53) | 0.255 |
Gender | ||||||
Male | 87.8% | 75.60% | reference | reference | ||
Female | 91.32% | 80.87% | 0.69(0.40~1.18) | 0.181 | 0.72(0.41~1.25) | 0.243 |
Tumor location | ||||||
Stomach | 90.78% | 81.16% | reference | reference | ||
Non-stomach | 86.79% | 72.53% | 1.95(1.16~3.30) | 0.012 | 1.46(0.85~2.52) | 0.171 |
Tumor size(cm) | ||||||
≤5 | 94.86% | 86.26% | reference | reference | ||
>5 | 81.77% | 65.76% | 3.18(1.84~5.50) | <0.001 | 2.06(1.16~3.68) | 0.014 |
Necrosis of tumor | ||||||
No | 94.63% | 87.28% | reference | reference | ||
Yes | 77.49% | 58.83% | 3.93(2.31~6.68) | <0.001 | 2.60(1.44~4.71) | 0.002 |
Mitotic index (per 50 HPF) | ||||||
≤5 | 95.35% | 87.26% | reference | reference | ||
>5 | 79.41% | 62.15% | 2.93(1.73~4.97) | <0.001 | 1.99(1.11~3.55) | 0.020 |
NIH risk grade | ||||||
Extremely low or low | 98.89% | 98.89% | reference | |||
Moderate or high | 83.85% | 64.90% | 8.89(3.53~22.36) | <0.001 | ||
SOCS6 expression | ||||||
High | 94.81% | 84.79% | reference | reference | ||
Low | 85.62% | 73.30% | 2.20(1.22~3.98) | 0.009 | 2.10(1.14~3.89) | 0.018 |