Fig. 2
From: SOX11 is a sensitive and specific marker for pulmonary high-grade neuroendocrine tumors
Electron photomicrograph of SOX11+ large cell carcinoma with neuroendocrine morphology. A, The tumor cell is rich in euchromatin and has distinct nucleolus with large nuclei (uranyl acetate and lead citrate, × 5000). B, Cytoplasmic dense-core (neurosecretory) granules surrounded by a transparent envelope (synaptic protein) within the cytoplasm are observed (As indicated by the white arrow) (uranyl acetate and lead citrate, × 15,000)