Skip to main content

Table 3 Immunoreactivity for Neuroendocrine Markers in SCLC

From: SOX11 is a sensitive and specific marker for pulmonary high-grade neuroendocrine tumors

Markers

No. of Cases

Positive markers

% of Cases

All negative

5

 

6

1 positive

9

1: CD56+

11

3: SOX11+

 

5: INSM1+

 

2 positive

6

1: CD56+, SYN+

8

1: SOX11+, CD56+

 

4: SOX11+, INSM1+

 

3 positive

10

1: SOX11+, SYN+, CGA+

13

1: SOX11+, CD56+, SYN+

 

2: CD56+, SYN+, INSM1+

 

6: CD56+, SYN+, CGA+

 

4 positive

20

1: SOX11+, CD56+, SYN+, CGA+

25

5: SOX11+, CD56+, SYN+, INSM1+

 

14: CD56+, SYN+, CGA+, INSM1+

 

All positive

29

 

37

Total no.

79a

  
  1. Abbreviations: SCLC, small cell lung carcinoma; INSM1, Insulinoma-associated protein 1; SYN, synaptophysin; CGA, chromogranin A
  2. aOne hundred and twenty cases were excluded from the 199 cases of SCLC because immunohistochemical staining was not performed for all markers
Back to article page

Diagnostic Pathology

ISSN: 1746-1596

Contact us