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Table 4 Comparison of UPK2 status detected by IHC and RNAscope in different UC tissues

From: Comparison of RNAscope and immunohistochemistry for evaluation of the UPK2 status in urothelial carcinoma tissues

UC Type

 

Positivity (%)

P value

BUC

IHC

103/172 (59.9)

0.092

RNAscope

116/172 (67.4)

 

Conventional BUC

IHC

87/127 (68.5)

0.511

RNAscope

92/127 (72.4)

 

Variant BUC

IHC

16/45 (35.6)

0.057

RNAscope

24/45 (53.3)

 

UTUC

IHC

19/24 (79.2)

1.000

RNAscope

18/24 (75.0)

 

Metastatic UC

IHC

15/23 (65.2)

1.000

RNAscope

15/23 (65.2)

 
  1. Abbreviations: IHC, immunohistochemistry; UC, urothelial carcinoma; BUC, bladder urothelial carcinoma; UTUC, upper tract urothelial carcinoma