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Fig. 2 | Diagnostic Pathology

Fig. 2

From: PIK3CA mutation correlates with mTOR pathway expression but not clinical and pathological features in Fibro-adipose vascular anomaly (FAVA)

Fig. 2

Histology and immunohistochemical analysis of FAVA. A-H Representative histological findings in PIK3CA-mutation case (A-D) and PIK3CA-wild type (wt) case (E-H). Vascular malformation and adipose and dense fibrous tissue (A, E; lower magnification and B, F; higher magnification). Clusters of vascular channels with thin-walled back-to-back blood-filled sacs (C, G). Nerve containing enlarged vessels (D, H arrows). I Serial sections of a nerve containing enlarged vessels (H) stained for S100, CD31, CD34, PROX1, and D20-40 (arrows indicated abnormal vessels in nerve)

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Diagnostic Pathology

ISSN: 1746-1596

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